The Interwetten Honda MotoGP team have revealed they will quit top-flight racing after this weekend's season finale in Valencia.
They will concentrate on Moto2 and 125cc racing next season in the hope of returning to MotoGP in 2012.
Rider Hiroshi Aoyama is expected to join the San Carlo Gresini Honda team.
"It is a pity that the team cannot continue. I had a really good time and I want to thank the team for all they did for me," said the Japanese rider.
Aoyama, the last champion of the old 250cc class, joined the Interwetten MotoGP team full of hope for his debut in the elite category.
But his season was rocked by a serious back injury suffered at the British Grand Prix at Silverstone in June, and his best result was a seventh-placed finish in Malaysia last month.
With one race of the 2010 season remaining, he lies 15th out of 21 riders in the world championship, with a total of 51 points.
Source: http://news.bbc.co.uk